MIR4645

Across TCGA pan-cancer cohorts, MIR4645 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MIR4645 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher MIR4645 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MIR4645 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

UCS, HNSC, and ACC are the cancer types where MIR4645 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.732	0.257	<.001	106	view →
HNSC	DFS	Quartile	IV	0.497	0.244	.002	61	view →
ACC	DFS	Tertile	IV	0.100	0.480	.005	45	view →
BLCA	OS	Quartile	III,IV	0.767	0.588	.002	37	view →
LUSC	OS	Quartile	All	0.717	0.833	.002	36	view →
KIRC	DFS	Quartile	II,III,IV	0.243	0.646	.001	26	view →
SKCM	DFS	Median	III,IV	0.351	0.173	.005	24	view →
BRCA	OS	Tertile	III,IV	0.964	0.851	.002	24	view →
KICH	DFS	Quartile	III,IV	0.885	0.169	.004	20	view →
LAML	DFS	Median	All	0.509	0.261	.004	18	view →
PCPG	DFS	Quartile	All	0.341	0.897	.010	18	view →
READ	OS	Median	II,III,IV	1.000	0.850	.009	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MIR4645–UCS (OS)

Open the UCS breakdown →