Across TCGA patient cohorts, MIR454 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,498 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIR454-associated proteins across cancer lineages are RFC2, SRRT, and MED1. Each is linked with MIR454 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIR454-to-partner and partner-to-MIR454 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR454→partner) and Y-score (partner→MIR454) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RFC2 →	+0.346	+0.780	.005	.005	3	5
GBM	SRRT →	+0.314	+0.876	<.001	.003	3	5
LSCC	MED1 →	+0.177	+0.622	<.001	<.001	3	5
GBM	RFC3 →	+0.363	+1.024	<.001	<.001	3	4
LSCC	SART1 →	+0.246	+0.853	.001	<.001	3	4
GBM	SF3B2 →	+0.263	+0.917	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,498 associations by consensus.

Exploration

MIR454 survival (RNA) · tumor vs normal (RNA) · all MIR454 data types