MIR4530

Across TCGA pan-cancer cohorts, MIR4530 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of MIR4530’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where MIR4530 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR4530 is over-expressed in tumor, although a few such as BLCA and UCEC show the opposite, repressed pattern.

BLCA, UCEC, and HNSC are the cancer types where MIR4530 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4530 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	IV	−1.874	<.001	9	view →
UCEC	All	II,III,IV	−1.311	.001	8	view →
HNSC	All	All	−0.415	.003	8	view →
STAD	All	II,III,IV	−0.964	.001	7	view →
LUSC	All	II,III,IV	−0.921	<.001	6	view →
LUAD	Female	All	−0.856	<.001	6	view →
BRCA	All	All	−0.759	<.001	6	view →
CHOL	All	II,III,IV	−1.145	.004	2	view →
THCA	Female	All	−0.525	.003	2	view →
READ	Female	All	−0.878	.005	1	view →
KIRC	Male	II,III,IV	+0.346	.045	1	view →
COAD	Female	All	−0.300	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

MIR4530–BLCA

Open the BLCA breakdown →