MIR4526

Across TCGA pan-cancer cohorts, MIR4526 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MIR4526 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MIR4526 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4526 expression acts as an unfavorable survival marker, although some lineages such as ESCA and THYM show a favorable association.

ACC, CESC, and MESO are the cancer types where MIR4526 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.075	0.635	<.001	81	view →
CESC	OS	Tertile	II,III,IV	0.114	0.573	.001	48	view →
MESO	DFS	Tertile	II,III,IV	0.155	0.419	.005	45	view →
READ	DFS	Tertile	III,IV	0.178	0.769	<.001	30	view →
ESCA	OS	Median	III,IV	0.573	0.308	.001	20	view →
THYM	OS	Tertile	All	1.000	0.776	.017	18	view →
PAAD	OS	Tertile	II,III,IV	0.243	0.415	.011	18	view →
BLCA	OS	Tertile	IV	0.074	0.599	<.001	18	view →
KIRP	OS	Tertile	II,III,IV	0.208	0.782	.004	18	view →
LIHC	OS	Tertile	III,IV	0.118	0.560	.002	18	view →
SKCM	DFS	Tertile	III,IV	0.188	0.660	.003	15	view →
BRCA	OS	Quartile	II,III,IV	0.986	0.946	.013	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MIR4526–ACC (DFS)

Open the ACC breakdown →