MIR4522

Across TCGA pan-cancer cohorts, MIR4522 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR4522 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher MIR4522 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4522 expression acts as an unfavorable survival marker.

LUSC, READ, and KIRC are the cancer types where MIR4522 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	II,III,IV	0.417	0.738	<.001	81	view →
READ	DFS	Tertile	All	0.027	0.845	<.001	51	view →
KIRC	OS	Tertile	II,III,IV	0.520	0.737	.008	42	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	36	view →
LGG	DFS	Tertile	All	0.226	0.454	.003	33	view →
UVM	OS	Tertile	III,IV	0.253	0.706	.012	18	view →
ESCA	OS	Tertile	All	0.597	0.870	.019	18	view →
UCEC	DFS	Tertile	All	0.828	0.900	.019	12	view →
THYM	DFS	Tertile	III,IV	0.205	0.774	.007	9	view →
KICH	OS	Tertile	All	0.758	0.939	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR4522–LUSC (DFS)

Open the LUSC breakdown →