MIR4516

Across TCGA patient cohorts, MIR4516 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,275 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4516-associated GO terms across cancer lineages are Positive regulation of chromosome organization, Positive regulation of canonical Wnt signaling pathway, and Methylation. Each is linked with MIR4516 in more than 15 cancer types. Because this analysis shows association rather than direction, both MIR4516-to-partner and partner-to-MIR4516 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome organization grouped by MIR4516-low versus MIR4516-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4516→partner) and Y-score (partner→MIR4516) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of chromosome organization →	+0.050	+0.429	<.001	<.001	3	16
STAD	Positive regulation of canonical Wnt signaling pathway →	+0.040	+0.392	<.001	<.001	3	15
STAD	Methylation →	+0.034	+0.428	<.001	<.001	3	15
ESCA	Positive regulation of plasma membrane bounded cell projection assembly →	+0.054	+0.488	<.001	<.001	3	15
ESCA	Regulation of organelle assembly →	+0.040	+0.344	<.001	<.001	3	15
ESCA	Nucleotide-excision repair →	+0.055	+0.602	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,275 associations by consensus.

Positive regulation of chromosome organization by MIR4516 expression — ESCA

Explore this box plot interactively →