MIR4512

Across TCGA pan-cancer cohorts, MIR4512 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MIR4512 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher MIR4512 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4512 expression acts as an unfavorable survival marker, although some lineages such as ACC and THYM show a favorable association.

UVM, MESO, and DLBC are the cancer types where MIR4512 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Quartile	All	0.319	1.000	<.001	43	view →
MESO	DFS	Median	All	0.207	0.635	<.001	27	view →
DLBC	DFS	Quartile	All	0.514	0.916	.003	27	view →
KICH	OS	Median	All	0.857	0.983	.011	25	view →
ACC	OS	Median	IV	0.906	0.476	.008	19	view →
KIRP	DFS	Tertile	IV	0.154	0.548	<.001	18	view →
COAD	OS	Median	All	0.832	0.898	.006	17	view →
THCA	OS	Median	II,III,IV	0.568	1.000	.007	17	view →
PRAD	DFS	Median	All	0.851	0.916	.017	16	view →
KIRC	DFS	Tertile	III,IV	0.321	0.578	.010	12	view →
SKCM	OS	Tertile	II,III,IV	0.763	0.889	.012	9	view →
LAML	DFS	Tertile	All	0.481	0.718	.015	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MIR4512–UVM (OS)

Open the UVM breakdown →