Q-omics provides the consensus-scored MIR4512 profile across patient tissues and cancer cell-line models. MIR4512 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, MIR4512 is differentially expressed in 3, with the highest sampling consensus in THCA. Additionally, MIR4512 RNA expression shows 14,728 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight UVM, and THCA as cancer lineages where MIR4512 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4512 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4512 survival associations across molecular data types. MIR4512 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4512 RNA expression–survival associations across cancer types. High MIR4512 expression shows unfavorable associations in UVM, MESO, DLBC, KICH and KIRP, but favorable associations in ACC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for MIR4512 RNA expression.
This table summarizes MIR4512 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4512. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4512 shows lower tumor expression in THCA and higher tumor expression in STAD and HNSC. The THCA box plot shows higher MIR4512 RNA expression in normal versus tumor tissue (log2 FC = −1.031, t-test p < 0.001).
This table shows molecular features associated with MIR4512 in patient tissues and cancer cell lines. In patient samples, MIR4512 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
