MIR4505

Across TCGA pan-cancer cohorts, MIR4505 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MIR4505 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR4505 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4505 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

HNSC, SARC, and STAD are the cancer types where MIR4505 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.267	0.590	.002	36	view →
SARC	DFS	Tertile	All	0.196	0.361	.002	36	view →
STAD	DFS	Tertile	II,III,IV	0.572	0.707	.006	27	view →
ACC	DFS	Tertile	III,IV	0.046	0.670	.001	27	view →
UCS	OS	Tertile	IV	0.844	0.250	.016	24	view →
UCEC	DFS	Tertile	IV	0.222	0.601	.039	18	view →
PCPG	OS	Tertile	All	0.810	0.978	.019	15	view →
THYM	OS	Quartile	III,IV	0.505	1.000	.005	9	view →
GBM	OS	Tertile	All	0.190	0.431	.009	9	view →
SKCM	DFS	Tertile	II,III,IV	0.463	0.237	.017	9	view →
READ	OS	Tertile	IV	0.077	1.000	.014	9	view →
LUSC	DFS	Tertile	III,IV	0.137	0.707	.020	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MIR4505–HNSC (OS)

Open the HNSC breakdown →