MIR4500HG

Across TCGA pan-cancer cohorts, MIR4500HG RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR4500HG data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher MIR4500HG RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MIR4500HG expression acts as an unfavorable survival marker, although some lineages such as KIRP and LGG show a favorable association.

KIRP, KICH, and LGG are the cancer types where MIR4500HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	0.930	0.498	.009	43	view →
KICH	OS	Tertile	All	0.769	0.973	.006	36	view →
LGG	OS	Tertile	All	0.936	0.845	<.001	33	view →
HNSC	OS	Tertile	IV	0.696	0.535	.009	31	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	22	view →
MESO	DFS	Quartile	IV	0.079	0.443	<.001	20	view →
UCEC	DFS	Quartile	All	0.779	0.862	.011	16	view →
THCA	OS	Tertile	IV	0.523	0.924	.001	15	view →
COAD	DFS	Quartile	II,III,IV	0.281	0.658	.008	12	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	12	view →
PAAD	DFS	Tertile	II,III,IV	0.584	0.357	.015	11	view →
READ	DFS	Tertile	IV	0.112	0.811	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR4500HG–KIRP (DFS)

Open the KIRP breakdown →