MIR4500HG

Across TCGA pan-cancer cohorts, MIR4500HG RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of MIR4500HG’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where MIR4500HG RNA is repressed in tumor relative to normal tissue. In most cancer types MIR4500HG is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and KIRP are the cancer types where MIR4500HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4500HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	II,III,IV	−0.251	<.001	9	view →
KICH	Female	All	−0.056	.002	6	view →
KIRP	Female	All	+0.697	.003	4	view →
UCEC	All	All	−0.351	.023	4	view →
KIRC	Female	All	+0.173	.024	3	view →
READ	All	All	−0.058	.015	2	view →
LUAD	Female	All	+0.141	.016	1	view →
LIHC	Male	III,IV	−0.032	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

MIR4500HG–THCA

Open the THCA breakdown →