MIR449C

Across TCGA patient cohorts, MIR449C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,243 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR449C-associated GO terms across cancer lineages are Microtubule-based transport, Epithelial tube formation, and Centrosome duplication. Each is linked with MIR449C in more than 7 cancer types. Because this analysis shows association rather than direction, both MIR449C-to-partner and partner-to-MIR449C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by MIR449C-low versus MIR449C-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR449C→partner) and Y-score (partner→MIR449C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Microtubule-based transport →	+0.084	+0.159	<.001	.002	3	8
ESCA	Epithelial tube formation →	+0.119	+0.116	<.001	.001	3	6
ESCA	Centrosome duplication →	+0.133	+0.148	<.001	.001	3	6
LUAD	Spermatid differentiation →	+0.027	+0.143	<.001	.003	3	6
ESCA	Specification of symmetry →	+0.050	+0.180	<.001	.002	3	6
ESCA	Maintenance of cell number →	+0.120	+0.109	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,243 associations by consensus.

Microtubule-based transport by MIR449C expression — ESCA

Explore this box plot interactively →