MIR4491

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MIR4491 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,491 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MIR4491-associated proteins across cancer lineages are SEPTIN1, RASAL3, and RASAL3_S988. Each is linked with MIR4491 in more than 5 cancer types. Because this analysis shows association rather than direction, both MIR4491-to-partner and partner-to-MIR4491 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIR4491 versus SEPTIN1 in CCRCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4491→partner) and Y-score (partner→MIR4491) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCSEPTIN1 →+0.709+0.264<.001.00336
CCRCCRASAL3 →+0.432+0.334<.001.00135
BRCARASAL3_S988 →+0.751+0.228<.001.00135
LUADSEPTIN1_S315 →+0.800+0.782<.001<.00135
CCRCCSEPTIN6 →+0.430+0.271<.001.00235
CCRCCCD2 →+0.764+0.397<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,491 associations by consensus.

MIR4491 vs SEPTIN1 — CCRCC

Per-sample scatter of MIR4491 vs SEPTIN1 in CCRCC (Pearson r = 0.45).

Explore this scatter interactively →

Exploration