MIR4491

Across TCGA pan-cancer cohorts, MIR4491 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR4491 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MIR4491 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4491 expression acts as an unfavorable survival marker, although some lineages such as STAD and OV show a favorable association.

BLCA, SKCM, and THCA are the cancer types where MIR4491 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	IV	0.106	0.593	<.001	54	view →
SKCM	OS	Tertile	II,III,IV	0.323	0.734	.029	24	view →
THCA	OS	Tertile	III,IV	0.196	0.888	<.001	24	view →
STAD	OS	Tertile	II,III,IV	0.805	0.505	.047	18	view →
READ	DFS	Tertile	IV	0.082	0.619	.001	18	view →
KICH	DFS	Tertile	All	0.121	0.867	.023	15	view →
OV	DFS	Tertile	All	0.423	0.153	.048	12	view →
THYM	DFS	Tertile	II,III,IV	0.091	0.842	.001	9	view →
LIHC	OS	Tertile	All	0.167	0.704	.041	9	view →
DLBC	DFS	Median	II,III,IV	0.670	1.000	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR4491–BLCA (OS)

Open the BLCA breakdown →