MIR4474

Across TCGA patient cohorts, MIR4474 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,369 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4474-associated GO terms across cancer lineages are Macromolecule methylation, Methylation, and Glycerophospholipid metabolic process. Each is linked with MIR4474 in more than 12 cancer types. Because this analysis shows association rather than direction, both MIR4474-to-partner and partner-to-MIR4474 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule methylation grouped by MIR4474-low versus MIR4474-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4474→partner) and Y-score (partner→MIR4474) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Macromolecule methylation →	+0.050	+0.379	<.001	<.001	3	13
STAD	Methylation →	+0.046	+0.376	<.001	<.001	3	12
STAD	Glycerophospholipid metabolic process →	+0.047	+0.382	<.001	<.001	3	12
STAD	Lipoprotein metabolic process →	+0.047	+0.330	<.001	<.001	3	11
STAD	Negative regulation of mRNA metabolic process →	+0.055	+0.392	<.001	<.001	3	11
STAD	Regulation of receptor-mediated endocytosis →	+0.040	+0.311	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,369 associations by consensus.

Macromolecule methylation by MIR4474 expression — STAD

Explore this box plot interactively →