MIR4474

Across TCGA pan-cancer cohorts, MIR4474 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR4474 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR4474 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4474 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

KIRC, SARC, and BRCA are the cancer types where MIR4474 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	II,III,IV	0.147	0.513	.007	48	view →
SARC	OS	Tertile	All	0.202	0.750	<.001	45	view →
BRCA	DFS	Tertile	All	0.890	0.951	.012	24	view →
READ	OS	Tertile	III,IV	0.287	0.772	.030	24	view →
STAD	DFS	Quartile	IV	0.137	0.447	.005	18	view →
PCPG	DFS	Tertile	All	0.535	0.936	<.001	18	view →
THCA	OS	Tertile	All	0.966	0.984	.002	12	view →
PAAD	OS	Tertile	All	0.368	0.654	.030	9	view →
COAD	OS	Tertile	IV	0.140	0.657	.035	9	view →
ESCA	DFS	Tertile	III,IV	0.457	0.263	.046	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR4474–KIRC (DFS)

Open the KIRC breakdown →