MIR4458HG

Across TCGA patient cohorts, MIR4458HG RNA expression is significantly associated with the go_rna of many other GO terms, with 6,658 significant associations in total. THCA shows the largest number of these associations.

The most reproducible MIR4458HG-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, Cytochrome complex assembly, and Mitochondrial transcription. Each is linked with MIR4458HG in more than 17 cancer types. Because this analysis shows association rather than direction, both MIR4458HG-to-partner and partner-to-MIR4458HG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by MIR4458HG-low versus MIR4458HG-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4458HG→partner) and Y-score (partner→MIR4458HG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial respiratory chain complex assembly →	+0.037	+0.435	.002	<.001	1	18
KICH	Cytochrome complex assembly →	+0.046	+1.194	<.001	.002	3	14
UVM	Mitochondrial transcription →	+0.068	+1.042	<.001	<.001	3	14
UVM	Positive regulation of mitochondrial translation →	+0.049	+0.915	<.001	.003	3	13
UVM	Respiratory chain complex IV assembly →	+0.056	+1.363	<.001	<.001	3	13
STAD	Mitochondrial gene expression →	+0.031	+0.321	.009	.005	1	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,658 associations by consensus.

Mitochondrial respiratory chain complex assembly by MIR4458HG expression — STAD

Explore this box plot interactively →