MIR4445

Across TCGA patient cohorts, MIR4445 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,838 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4445-associated GO terms across cancer lineages are DNA replication, Amino acid catabolic process, and Cerebral cortex development. Each is linked with MIR4445 in more than 4 cancer types. Because this analysis shows association rather than direction, both MIR4445-to-partner and partner-to-MIR4445 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by MIR4445-low versus MIR4445-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4445→partner) and Y-score (partner→MIR4445) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	DNA replication →	+0.192	+0.119	<.001	<.001	3	5
STAD	Amino acid catabolic process →	+0.095	+0.106	<.001	<.001	3	5
STAD	Cerebral cortex development →	+0.122	+0.097	<.001	<.001	3	5
STAD	Signal transduction in response to DNA damage →	+0.184	+0.104	<.001	<.001	3	5
STAD	Negative regulation of DNA recombination →	+0.140	+0.115	<.001	<.001	3	5
STAD	Negative regulation of organelle assembly →	+0.140	+0.100	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,838 associations by consensus.

DNA replication by MIR4445 expression — STAD

Explore this box plot interactively →