MIR4440

Across TCGA patient cohorts, MIR4440 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,532 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MIR4440-associated GO terms across cancer lineages are Regulation of RNA splicing, Rhythmic process, and Obsolete histone H3-K4 methylation. Each is linked with MIR4440 in more than 12 cancer types. Because this analysis shows association rather than direction, both MIR4440-to-partner and partner-to-MIR4440 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by MIR4440-low versus MIR4440-high in KIRC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4440→partner) and Y-score (partner→MIR4440) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Regulation of RNA splicing →	+0.044	+0.047	<.001	<.001	3	11
UCS	Rhythmic process →	+0.033	+0.203	.004	.008	1	13
ESCA	Obsolete histone H3-K4 methylation →	+0.055	+0.307	.002	.001	3	11
ESCA	P-body assembly →	+0.054	+0.355	.001	<.001	3	11
ESCA	Regulation of telomere maintenance →	+0.054	+0.408	.002	<.001	3	11
ESCA	Macromolecule deacylation →	+0.042	+0.382	.003	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,532 associations by consensus.

Regulation of RNA splicing by MIR4440 expression — KIRC

Explore this box plot interactively →