Q-omics provides the consensus-scored MIR4439 profile across patient tissues and cancer cell-line models. MIR4439 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, MIR4439 is differentially expressed in 1, with the highest sampling consensus in BRCA. Additionally, MIR4439 RNA expression shows 13,000 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight MESO, BRCA, and LSCC as cancer lineages where MIR4439 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4439 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4439 survival associations across molecular data types. MIR4439 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4439 RNA expression–survival associations across cancer types. High MIR4439 expression shows unfavorable associations in MESO, THCA, LUSC, COAD, OV and SKCM. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for MIR4439 RNA expression.
This table summarizes MIR4439 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4439. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4439 shows higher tumor expression in BRCA. The BRCA box plot shows higher MIR4439 RNA expression in tumor versus normal tissue (log2 FC = +0.171, t-test p = .020).
This table shows molecular features associated with MIR4439 in patient tissues and cancer cell lines. In patient samples, MIR4439 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
