MIR4435-2HG

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR4435-2HG Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated MIR4435-2HG data layer compared with 22 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIR4435-2HG Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4435-2HG expression acts as an unfavorable survival marker.

UCEC are the cancer types where MIR4435-2HG Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianIII,IV0.0610.588.01812view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

MIR4435-2HG–UCEC (OS)

Kaplan–Meier survival curve for MIR4435-2HG mutant vs wild-type samples in UCEC.

Open the UCEC breakdown →

Exploration