MIR4435-2

Across TCGA pan-cancer cohorts, MIR4435-2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR4435-2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR4435-2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4435-2 is over-expressed in tumor.

BRCA, HNSC, and ESCA are the cancer types where MIR4435-2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4435-2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.133	.041	2	view →
HNSC	All	II,III,IV	+0.091	.045	2	view →
ESCA	All	All	+0.313	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

MIR4435-2–BRCA

Open the BRCA breakdown →