MIR4435-1

Across TCGA pan-cancer cohorts, MIR4435-1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MIR4435-1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MIR4435-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4435-1 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

BLCA, PAAD, and LUSC are the cancer types where MIR4435-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.393	0.717	<.001	162	view →
PAAD	DFS	Tertile	All	0.275	0.502	.009	63	view →
LUSC	DFS	Tertile	All	0.190	0.801	<.001	60	view →
GBM	OS	Tertile	All	0.180	0.421	<.001	45	view →
LGG	OS	Tertile	All	0.280	0.813	<.001	45	view →
READ	OS	Tertile	All	0.166	0.830	<.001	42	view →
DLBC	DFS	Tertile	II,III,IV	0.065	0.829	<.001	36	view →
HNSC	DFS	Tertile	All	0.306	0.564	.023	27	view →
OV	DFS	Tertile	IV	0.286	0.499	.015	18	view →
KIRC	DFS	Tertile	IV	0.255	0.511	.034	12	view →
BRCA	DFS	Tertile	All	0.928	0.950	.022	12	view →
ESCA	OS	Median	III,IV	0.552	0.316	.021	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MIR4435-1–BLCA (OS)

Open the BLCA breakdown →