MIR4420

Across TCGA pan-cancer cohorts, MIR4420 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR4420 data layer.

The strongest signal is observed in thymoma (THYM), where higher MIR4420 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4420 expression acts as an unfavorable survival marker, although some lineages such as LUAD and BRCA show a favorable association.

THYM, UVM, and KIRC are the cancer types where MIR4420 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	DFS	Quartile	All	0.704	0.942	<.001	77	view →
UVM	DFS	Tertile	All	0.148	0.776	<.001	63	view →
KIRC	DFS	Tertile	All	0.525	0.692	<.001	39	view →
UCS	DFS	Tertile	II,III,IV	0.175	0.471	.031	36	view →
LUAD	OS	Tertile	II,III,IV	0.750	0.474	.001	29	view →
BRCA	OS	Median	All	0.980	0.949	.001	28	view →
PRAD	DFS	Tertile	All	0.814	0.907	.003	24	view →
LGG	DFS	Tertile	All	0.307	0.439	.004	16	view →
OV	DFS	Quartile	III,IV	0.448	0.559	.008	16	view →
COAD	DFS	Tertile	II,III,IV	0.505	0.680	.020	12	view →
LAML	DFS	Median	All	0.479	0.662	.020	12	view →
STAD	DFS	Median	All	0.268	0.490	.004	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR4420–THYM (DFS)

Open the THYM breakdown →