MIR4420

Across TCGA pan-cancer cohorts, MIR4420 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MIR4420’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR4420 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4420 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

KIRC, LUSC, and LUAD are the cancer types where MIR4420 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4420 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.517	<.001	10	view →
LUSC	All	All	−0.624	<.001	6	view →
LUAD	All	IV	−1.520	.041	2	view →
STAD	All	II,III,IV	+0.678	.030	2	view →
LIHC	Male	All	−0.216	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MIR4420–KIRC

Open the KIRC breakdown →