MIR4306

Across TCGA pan-cancer cohorts, MIR4306 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated MIR4306 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIR4306 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4306 expression acts as an unfavorable survival marker, although some lineages such as ESCA and KIRC show a favorable association.

UCEC, THCA, and GBM are the cancer types where MIR4306 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.857	0.930	.003	60	view →
THCA	OS	Tertile	All	0.897	0.977	<.001	42	view →
GBM	DFS	Tertile	All	0.092	0.245	.026	18	view →
SKCM	DFS	Tertile	III,IV	0.111	0.601	<.001	15	view →
ESCA	DFS	Median	III,IV	0.527	0.319	.013	15	view →
UVM	DFS	Tertile	III,IV	0.071	0.636	<.001	9	view →
BLCA	OS	Tertile	IV	0.225	0.490	.043	9	view →
LIHC	OS	Tertile	All	0.313	0.681	.016	9	view →
KIRC	DFS	Tertile	All	0.929	0.860	.036	6	view →
STAD	OS	Quartile	III,IV	0.532	0.678	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

MIR4306–UCEC (OS)

Open the UCEC breakdown →