MIR4281

Across TCGA patient cohorts, MIR4281 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,919 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MIR4281-associated GO terms across cancer lineages are Urogenital system development, Maternal placenta development, and Regulation of calcium ion export across plasma membrane. Each is linked with MIR4281 in more than 2 cancer types. Because this analysis shows association rather than direction, both MIR4281-to-partner and partner-to-MIR4281 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Urogenital system development grouped by MIR4281-low versus MIR4281-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4281→partner) and Y-score (partner→MIR4281) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Urogenital system development →	+0.060	+0.043	<.001	.002	3	2
STAD	Maternal placenta development →	+0.073	+0.075	<.001	<.001	3	2
HNSC	Regulation of calcium ion export across plasma membrane →	+0.060	+0.050	<.001	.004	2	3
HNSC	Amyloid fibril formation →	+0.078	+0.030	<.001	.002	3	2
HNSC	Interleukin-1 production →	+0.047	+0.055	<.001	<.001	3	2
ESCA	Glucan metabolic process →	+0.065	+0.135	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,919 associations by consensus.

Urogenital system development by MIR4281 expression — HNSC

Explore this box plot interactively →