Q-omics provides the consensus-scored MIR4281 profile across patient tissues and cancer cell-line models. MIR4281 expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in SKCM. Additionally, MIR4281 RNA expression shows 3,617 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight SKCM, and LUSC as cancer lineages where MIR4281 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR4281 survival associations across molecular data types. MIR4281 RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR4281 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	SKCM (54)	view →

This table ranks reproducible MIR4281 RNA expression–survival associations across cancer types. High MIR4281 expression shows unfavorable associations in SKCM, LAML, CESC, COAD, LIHC and BRCA. The SKCM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for MIR4281 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.239	0.784	<.001	54	view →
LAML	DFS	Tertile	All	0.028	0.572	<.001	36	view →
CESC	DFS	Tertile	All	0.174	0.740	.011	18	view →
COAD	DFS	Tertile	IV	0.028	0.496	<.001	18	view →
LIHC	DFS	Tertile	All	0.043	0.543	<.001	18	view →
BRCA	OS	Tertile	All	0.718	0.925	.021	12	view →

Pink = unfavorable, green = favorable. all 7 lineages →

MIR4281-SKCM (OS)

Kaplan–Meier survival curve for MIR4281 RNA expression in SKCM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR4281 in patient tissues and cancer cell lines. In patient samples, MIR4281 shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	3,617	LUSC (2345)	view →
Function (RNA)	1,919	HNSC (1351)	view →