MIR4261

Across TCGA patient cohorts, MIR4261 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,184 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MIR4261-associated proteins across cancer lineages are MCM2, RACGAP1, and MSH6. Each is linked with MIR4261 in more than 6 cancer types. Because this analysis shows association rather than direction, both MIR4261-to-partner and partner-to-MIR4261 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIR4261 versus MCM2 in GBM, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4261→partner) and Y-score (partner→MIR4261) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCM2 →	+0.538	+0.934	<.001	<.001	3	7
UCEC	RACGAP1 →	+0.483	+1.310	.001	<.001	3	7
LSCC	MSH6 →	+0.540	+1.076	<.001	.002	3	7
LUAD	RFC1_T506 →	+0.848	+0.692	<.001	<.001	3	6
GBM	SMC2 →	+0.497	+1.101	<.001	<.001	3	6
HNSC	SMC4 →	+0.489	+1.541	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,184 associations by consensus.

MIR4261 vs MCM2 — GBM

Explore this scatter interactively →