MIR4258

Across TCGA patient cohorts, MIR4258 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,993 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MIR4258-associated proteins across cancer lineages are PARP1, SF3B6, and RFC3. Each is linked with MIR4258 in more than 7 cancer types. Because this analysis shows association rather than direction, both MIR4258-to-partner and partner-to-MIR4258 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MIR4258 versus PARP1 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4258→partner) and Y-score (partner→MIR4258) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PARP1 →	+0.488	+1.153	<.001	<.001	3	8
GBM	SF3B6 →	+0.334	+1.012	<.001	<.001	3	6
GBM	RFC3 →	+0.358	+0.828	.001	<.001	3	6
LSCC	RRP36_S73 →	+0.810	+0.718	<.001	<.001	3	6
COAD	CTR9 →	+0.231	+0.907	<.001	<.001	3	6
GBM	DHX9 →	+0.286	+1.013	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,993 associations by consensus.

MIR4258 vs PARP1 — HNSC

Explore this scatter interactively →