MIR4254

Across TCGA pan-cancer cohorts, MIR4254 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR4254 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MIR4254 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR4254 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

ACC, MESO, and KICH are the cancer types where MIR4254 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.599	0.890	<.001	180	view →
MESO	OS	Tertile	All	0.052	0.528	.016	54	view →
KICH	DFS	Tertile	All	0.102	0.848	.004	39	view →
COAD	DFS	Tertile	All	0.141	0.522	.019	36	view →
BRCA	DFS	Tertile	II,III,IV	0.831	0.898	.008	33	view →
LGG	DFS	Quartile	All	0.745	0.859	.001	32	view →
PRAD	OS	Tertile	All	0.921	0.996	.003	30	view →
BLCA	DFS	Tertile	All	0.181	0.512	.005	18	view →
THCA	OS	Tertile	IV	0.720	0.986	.001	18	view →
HNSC	DFS	Tertile	II,III,IV	0.843	0.317	.040	18	view →
TGCT	OS	Tertile	II,III,IV	0.752	1.000	.019	18	view →
LIHC	OS	Tertile	All	0.167	0.688	.035	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR4254–ACC (OS)

Open the ACC breakdown →