MIR4254

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR4254 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR4254’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR4254 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4254 is over-expressed in tumor.

BRCA and LUSC are the cancer types where MIR4254 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4254 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAFemaleII,III,IV+0.186.0016view →
LUSCAllAll+0.056.0431view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

MIR4254–BRCA

Tumor-vs-normal expression box plot for MIR4254 RNA in BRCA.

Open the BRCA breakdown →

Exploration