Across TCGA patient cohorts, MIR409 mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR409-associated genes across cancer lineages are CFL1P8, AP1B1P1, and VDAC2P4. Each is linked with MIR409 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR409-to-partner and partner-to-MIR409 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR409→partner) and Y-score (partner→MIR409) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CFL1P8 →	+0.179	+4.500	<.001	.005	3	1
SKCM	AP1B1P1 →	+0.143	+4.296	<.001	.008	3	1
SKCM	VDAC2P4 →	+0.069	+4.661	.006	.004	3	1
SKCM	CTDSPL2P1 →	+0.027	+4.680	<.001	.007	3	1
SKCM	MMEL1-AS1 →	+0.270	+4.594	<.001	.008	3	1
SKCM	ELAVL4-AS1 →	+0.251	+4.440	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

MIR409 survival (RNA) · tumor vs normal (RNA) · all MIR409 data types