MIR3945HG

Across TCGA pan-cancer cohorts, MIR3945HG RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MIR3945HG data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR3945HG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR3945HG expression acts as an unfavorable survival marker, although some lineages such as SKCM and LIHC show a favorable association.

KIRC, THYM, and LGG are the cancer types where MIR3945HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.534	0.721	.001	56	view →
THYM	OS	Tertile	All	0.727	0.941	.009	41	view →
LGG	OS	Quartile	All	0.788	0.929	<.001	31	view →
SKCM	DFS	Median	II,III,IV	0.324	0.201	.002	29	view →
LIHC	DFS	Tertile	All	0.640	0.462	.006	25	view →
LUSC	OS	Tertile	All	0.309	0.448	.013	18	view →
LUAD	DFS	Median	IV	0.333	0.648	.013	18	view →
OV	DFS	Median	II,III,IV	0.411	0.350	.027	16	view →
BRCA	OS	Tertile	IV	0.194	0.933	.007	13	view →
GBM	DFS	Quartile	All	0.161	0.423	.007	12	view →
MESO	OS	Median	II,III,IV	0.204	0.480	.028	12	view →
LAML	DFS	Quartile	All	0.295	0.524	.027	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MIR3945HG–KIRC (DFS)

Open the KIRC breakdown →