MIR3945HG

Across TCGA pan-cancer cohorts, MIR3945HG RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of MIR3945HG’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where MIR3945HG RNA is repressed in tumor relative to normal tissue. In most cancer types MIR3945HG is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and COAD are the cancer types where MIR3945HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR3945HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−2.529	<.001	9	view →
LUSC	Female	II,III,IV	−3.612	<.001	8	view →
COAD	All	II,III,IV	+0.247	.001	8	view →
KIRC	All	All	+0.140	<.001	8	view →
HNSC	All	II,III,IV	+0.777	<.001	7	view →
STAD	All	All	+0.581	<.001	6	view →
THCA	Male	All	+0.370	.001	6	view →
BRCA	All	II,III,IV	−0.181	.002	6	view →
LIHC	All	All	−0.228	.012	4	view →
KICH	All	All	−0.178	.023	2	view →
PRAD	All	All	+0.075	.024	2	view →
ESCA	Female	All	+1.110	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

MIR3945HG–LUAD

Open the LUAD breakdown →