MIR378B

Across TCGA pan-cancer cohorts, MIR378B RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated MIR378B data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher MIR378B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR378B expression acts as an unfavorable survival marker, although some lineages such as LIHC show a favorable association.

COAD, UCEC, and CHOL are the cancer types where MIR378B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.039	0.851	<.001	54	view →
UCEC	DFS	Tertile	All	0.499	0.703	.002	42	view →
CHOL	DFS	Quartile	All	0.119	0.577	.003	18	view →
PRAD	DFS	Tertile	All	0.732	0.936	.012	18	view →
LGG	DFS	Tertile	All	0.780	0.875	.005	12	view →
THCA	DFS	Tertile	II,III,IV	0.151	0.678	.049	9	view →
PCPG	DFS	Quartile	All	0.570	0.920	.024	9	view →
ACC	DFS	Median	All	0.170	0.578	.007	8	view →
LIHC	DFS	Quartile	All	0.612	0.400	.022	7	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

MIR378B–COAD (OS)

Open the COAD breakdown →