MIR3680-2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MIR3680-2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MIR3680-2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MIR3680-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR3680-2 expression acts as an unfavorable survival marker, although some lineages such as BRCA and SKCM show a favorable association.

ACC, LIHC, and UVM are the cancer types where MIR3680-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.4940.834.00163view →
LIHCDFSTertileAll0.2530.560<.00163view →
UVMDFSTertileIII,IV0.1200.747.00157view →
THYMOSTertileAll0.4820.943<.00139view →
KIRPDFSTertileIV0.0880.502<.00136view →
BRCADFSTertileIII,IV0.7700.426.00730view →
SKCMDFSTertileIII,IV0.7570.546.01421view →
COADOSTertileIV0.1880.699.01318view →
CESCDFSTertileII,III,IV0.6250.816.01118view →
TGCTDFSTertileII,III,IV0.0880.917.01018view →
SARCOSTertileAll0.4270.834.00518view →
UCECDFSTertileAll0.8210.901.01418view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MIR3680-2–ACC (OS)

Kaplan–Meier survival curve for MIR3680-2 RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration