Across TCGA pan-cancer cohorts, MIR361 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of MIR361’s most consistent transcriptional readouts.

The strongest signal is observed in rectum adenocarcinoma (READ), where MIR361 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR361 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

READ, HNSC, and LUSC are the cancer types where MIR361 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR361 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
READ	All	III,IV	+0.660	<.001	2	view →
HNSC	All	IV	+0.141	.046	1	view →
LUSC	Female	All	−0.137	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: MIR361 RNA expression & survival · all MIR361 data types