Across TCGA pan-cancer cohorts, MIR328 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR328’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MIR328 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR328 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

COAD, PAAD, and ESCA are the cancer types where MIR328 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR328 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.321	.012	4	view →
PAAD	Female	All	−0.710	.036	2	view →
ESCA	All	II,III,IV	+0.605	.019	2	view →
THCA	Female	All	+0.091	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR328 RNA expression & survival · all MIR328 data types