Across TCGA patient cohorts, MIR325 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR325-associated genes across cancer lineages are RPS28P1, MTND6P12, and SULT1D1P. Each is linked with MIR325 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR325-to-partner and partner-to-MIR325 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR325→partner) and Y-score (partner→MIR325) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS28P1 →	+0.371	+5.027	<.001	.004	3	1
SKCM	MTND6P12 →	+0.079	+5.224	<.001	.007	3	1
SKCM	SULT1D1P →	+0.044	+4.979	.004	.009	3	1
UCEC	DUTP5 →	+0.232	+4.349	.001	.007	3	1
UCEC	MIR1207 →	+0.818	+4.661	.002	.004	3	1
UCEC	SNRPGP8 →	+0.342	+4.937	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

MIR325 survival (RNA) · tumor vs normal (RNA) · all MIR325 data types