Across TCGA pan-cancer cohorts, MIR3162 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of MIR3162’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where MIR3162 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR3162 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA and KIRC are the cancer types where MIR3162 tumor–normal differential expression is most reproducible.