MIR3135A

Across TCGA pan-cancer cohorts, MIR3135A RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MIR3135A data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR3135A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR3135A expression acts as an unfavorable survival marker, although some lineages such as LIHC and KIRP show a favorable association.

KIRC, READ, and THCA are the cancer types where MIR3135A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.466	0.671	<.001	106	view →
READ	OS	Tertile	All	0.535	0.931	<.001	78	view →
THCA	OS	Tertile	II,III,IV	0.820	0.965	<.001	57	view →
LUAD	DFS	Tertile	IV	0.511	0.978	<.001	54	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	41	view →
PAAD	OS	Tertile	II,III,IV	0.307	0.579	.005	18	view →
PRAD	DFS	Tertile	All	0.866	0.943	.009	18	view →
CESC	OS	Tertile	IV	0.095	0.592	.004	18	view →
LGG	DFS	Quartile	All	0.302	0.449	.001	16	view →
LIHC	OS	Tertile	III,IV	0.752	0.291	.021	12	view →
KIRP	DFS	Tertile	All	1.000	0.563	.025	9	view →
GBM	OS	Quartile	All	0.500	0.380	.024	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MIR3135A–KIRC (OS)

Open the KIRC breakdown →