MIR3130-2

Across TCGA pan-cancer cohorts, MIR3130-2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MIR3130-2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR3130-2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR3130-2 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

KIRC, ESCA, and GBM are the cancer types where MIR3130-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.486	0.664	.005	81	view →
ESCA	OS	Tertile	IV	0.135	0.568	.031	36	view →
GBM	DFS	Tertile	All	0.666	0.237	.005	36	view →
COAD	OS	Tertile	III,IV	0.167	0.548	.026	30	view →
LIHC	OS	Tertile	All	0.418	0.789	.005	21	view →
UCEC	OS	Tertile	All	0.756	0.878	.029	18	view →
THCA	DFS	Tertile	II,III,IV	0.817	0.912	.022	15	view →
SARC	OS	Tertile	All	0.258	0.527	.020	12	view →
KIRP	DFS	Tertile	All	0.369	0.634	.005	9	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
THYM	DFS	Tertile	All	0.366	0.747	.003	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MIR3130-2–KIRC (DFS)

Open the KIRC breakdown →