MIR3130-2

Across TCGA pan-cancer cohorts, MIR3130-2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR3130-2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MIR3130-2 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR3130-2 is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.

BRCA, COAD, and THCA are the cancer types where MIR3130-2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR3130-2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.249	.002	4	view →
COAD	Male	All	−0.240	.022	3	view →
THCA	Female	All	−0.173	.027	1	view →
LUAD	All	All	+0.165	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR3130-2–BRCA

Open the BRCA breakdown →