Across TCGA pan-cancer cohorts, MIR29B2CHG RNA is linked to patient survival in 30 of 34 cancer types, making it the most broadly survival-associated MIR29B2CHG data layer compared with 2 for mutation status.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR29B2CHG RNA is associated with better overall survival. In most high-consensus cancer types, elevated MIR29B2CHG expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.
HNSC, SKCM, and ACC are the cancer types where MIR29B2CHG RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.