Across TCGA pan-cancer cohorts, MIR26A1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR26A1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where MIR26A1 RNA is repressed in tumor relative to normal tissue. In most cancer types MIR26A1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and KICH are the cancer types where MIR26A1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR26A1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−0.421	.001	4	view →
LUSC	All	All	−0.316	<.001	4	view →
KICH	Male	II,III,IV	+0.420	.010	2	view →
THCA	All	All	−0.204	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: MIR26A1 RNA expression & survival · all MIR26A1 data types