MIR23C

Across TCGA pan-cancer cohorts, MIR23C RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated MIR23C data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIR23C RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MIR23C expression acts as an unfavorable survival marker, although some lineages such as HNSC and KIRC show a favorable association.

UCEC, KIRP, and HNSC are the cancer types where MIR23C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	IV	0.533	0.755	<.001	72	view →
KIRP	DFS	Tertile	All	0.811	0.937	<.001	65	view →
HNSC	DFS	Tertile	IV	0.792	0.612	.010	51	view →
STAD	DFS	Tertile	II,III,IV	0.426	0.657	<.001	45	view →
LIHC	OS	Tertile	All	0.640	0.792	.009	36	view →
KIRC	DFS	Tertile	IV	0.785	0.450	.003	33	view →
UVM	OS	Tertile	III,IV	0.452	0.933	.003	30	view →
UCS	DFS	Tertile	II,III,IV	0.626	0.180	.010	22	view →
PAAD	DFS	Tertile	All	0.460	0.222	.012	18	view →
ESCA	OS	Tertile	II,III,IV	0.105	0.867	.016	18	view →
PRAD	DFS	Tertile	All	0.884	0.944	.001	18	view →
SKCM	OS	Tertile	All	0.680	0.800	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

MIR23C–UCEC (OS)

Open the UCEC breakdown →