MIR23C

Across TCGA pan-cancer cohorts, MIR23C RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of MIR23C’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR23C RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR23C is over-expressed in tumor, although a few such as ESCA show the opposite, repressed pattern.

KIRC, LUAD, and COAD are the cancer types where MIR23C tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR23C RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	+0.652	<.001	11	view →
LUAD	All	All	+0.442	<.001	4	view →
COAD	All	All	+0.304	.008	4	view →
LUSC	All	All	+0.279	.001	3	view →
PRAD	All	All	+0.181	.004	2	view →
ESCA	All	All	−1.135	.029	1	view →
KIRP	Female	All	+0.294	.049	1	view →
LIHC	All	All	+0.086	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

MIR23C–KIRC

Open the KIRC breakdown →