MIR2278

Across TCGA pan-cancer cohorts, MIR2278 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated MIR2278 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MIR2278 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MIR2278 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

HNSC, TGCT, and KIRC are the cancer types where MIR2278 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.564	0.279	.003	138	view →
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	90	view →
KIRC	DFS	Tertile	III,IV	0.183	0.517	.001	42	view →
BRCA	DFS	Tertile	All	0.991	0.944	.021	36	view →
LUAD	OS	Tertile	All	0.912	0.663	<.001	36	view →
SKCM	DFS	Tertile	III,IV	0.239	0.664	.002	33	view →
THYM	DFS	Tertile	All	0.190	0.738	.001	18	view →
OV	OS	Tertile	III,IV	0.885	0.825	.031	12	view →
PAAD	OS	Median	III,IV	0.629	1.000	.022	9	view →
BLCA	OS	Tertile	III,IV	0.208	0.473	.041	9	view →
COAD	DFS	Tertile	IV	0.117	0.515	.021	9	view →
PCPG	OS	Tertile	All	0.772	0.966	.044	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

MIR2278–HNSC (OS)

Open the HNSC breakdown →