MIR2278

Across TCGA pan-cancer cohorts, MIR2278 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR2278’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where MIR2278 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR2278 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

ESCA, STAD, and UCEC are the cancer types where MIR2278 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR2278 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+1.025	<.001	4	view →
STAD	Female	III,IV	+0.730	<.001	4	view →
UCEC	All	IV	+1.085	.022	2	view →
KICH	All	III,IV	−0.540	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR2278–ESCA

Open the ESCA breakdown →